I have a question for someone who lives in or knows NYC?

okay, from penn station, take the A, C or E train that will take you to 8th ave, which is near times square, from there you can walk a few blocks to the empire state building and 5th avenue shopping. Then I would recommend to walk to rockefeller center and the WTC center. Then get back on the subway and head to ellis island last, because thats the furthest away. Just remember the A,C, E trains stay in heart of manhattan. If you have time I recommend also going to Grenich Village. Such a great experience if you have not been to NYC in a long time